Mutation discovery in mice by whole exome sequencing
December 2011
Authors:
Heather Fairfield, Griffith J Gilbert, Mary Barter, Rebecca R Corrigan, Michelle Curtain, Yueming Ding, Mark D’Ascenzo, Daniel J Gerhardt, Chao He, Wenhui Huang, Todd Richmond, Lucy Rowe, Frank J Probst,
David E Bergstrom, Stephen A Murray, Carol Bult, Joel Richardson, Benjamin T Kilew, Ivo Gut, Jorg Hager, Snaevar Sigurdsson, Evan Mauceli, Federica Di Palma, Kerstin Lindblad-Toh, Michael L Cunningham,
Timothy C Cox, Monica J Justice, Mona S Spector, Scott W Lowe, Thomas Albert, Leah Rae Donahue, Jeffrey Jeddeloh, Jay Shendure and Laura G Reinholdt
Info:
Materials and Methods: Illumina PE libraries were constructed and size selected at 430bp “tight” setting on Pippin Prep prior to enrichment PCR and hybridization capture for whole exome regions.
Citation:
Genome Biology 2011, 12:R86
Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
September 2011
Authors:
Laura G. Reinholdt, Yueming Ding, Griffith T. Gilbert, Anne Czechanski, Jeffrey P. Solzak, Randall J. Roper, Mark T. Johnson, Leah Rae Donahue, Cathleen Lutz, Muriel T. Davisson
Info:
Illumina PE libraries were constructed and size selected at 400bp “tight” setting on Pippin Prep prior to enrichment PCR and hybridization capture for genomic region surrounding the Down syndrome locus in mouse, to identify rearrangements in a much-studied Down’s syndrome model strain.
Citation:
Mamm Genome (2011) 22:685–691