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Sage Science
Sage Science
  • Technology
  • Products
    • TELL-Seq™ Bar Code Linked-read Library Kit

      Transposase insertion of bar-codes into NGS libraries

    • HLS2 HMW Library System

      Cas9 target selection of large genomic regions. HMW DNA extraction.

    • PippinHT DNA Size Selection System

      Up to 24 samples per run. Selects 100 bp – 1.5 kb. High Pass up to 40 kb.

    • BluePippin DNA Size Selection System

      Selects 100 bp – 50 kb. High Pass up to 40 kb.

    • Pippin Prep DNA Size Selection System

      Selects 100 bp – 1.5 kb.

    • SageELF Whole Sample Fractionation System

      DNA (up to 40 kb) or Proteins (up to 500 kDa).

    • Pippin Pulse Electrophoresis Power Supply

      Resolves DNA up to 400kb on a midi gel box.

  • Applications
    • Transposase Enzyme Linked Long-Read Sequencing

      Barcode linked reads for WGS, metagenomics, and CATCH

    • DNA Sequencing

      NGS sample prep for short-read and long-read platforms

    • RNA Sequencing

      Improve efficiency of RNA-seq workflows

    • HMW Target Capture

      HLS-CATCH uses Cas9 guide RNAs to capture genomic regions up to 500 Kb

    • Genotyping

      Massively parallel genotyping with ddRAD-seq

    • MicroRNA

      Highly accurate targeting for microRNAs and other small RNAs

    • Cell-Free DNA

      Isolate small cfDNA for study

    • Proteomics

      Whole-sample or targeted protein fractionation

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Tips and Applications

Archives

  • Targeted Phasing of 2-200 Kilobase DNA Fragments with a Short-Read Sequencer and a Single-Tube Linked-Read Library Method
  • AGBT23 Roundup!
  • Innovations in double digest restriction-site associated DNA sequencing (ddRAD-Seq) method for more efficient SNP identification
  • Utility of long-read sequencing for All of Us
  • Significance of HLA in the development of Graves’ orbitopathy
  • Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands
  • Large Cancer Pedigree Involving Multiple Cancer Genes including Likely Digenic MSH2 and MSH6 Lynch Syndrome (LS) and an Instance of Recombinational Rescue from LS
  • Optimising ddRAD sequencing for population genomic studies with ddgRADer
  • Heat selection enables highly scalable methylome profiling in cell-free DNA for noninvasive monitoring of cancer patients
  • rDNA array length is a major determinant of replicative lifespan in budding yeast
978-922-1832

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  • HLS2 HMW Library System
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