PippinHT DNA Size Selection System
Up to 24 samples per run. Selects 100 bp – 1.5 kb. High Pass up to 40 kb.
BluePippin DNA Size Selection System
Selects 100 bp – 50 kb. High Pass up to 40 kb.
Pippin Prep DNA Size Selection System
Selects 100 bp – 1.5 kb.
HLS2 HMW Library System
Cas9 target selection of large genomic regions. HMW DNA extraction.
SageELF Whole Sample Fractionation System
DNA (up to 40 kb) or Proteins (up to 500 kDa).
Pippin Pulse Electrophoresis Power Supply
Resolves DNA up to 400kb on a midi gel box.
TELL-Seq™ Bar Code Linked-read Library Kit
Transposase insertion of bar-codes into NGS libraries
CRISPR/Cas9 can be used to design targeted purification of large genomic regions or genes. This in vitro application with Cas9, termed CATCH, can enhance study of structural variation and provide valuable phasing information.
*Cas9-Assisted Targeting of CHromosome Segments
Jiang et. al., 2015, Nature Communications, doi:10.1038/ncomm9101
SageHLS vs HLS2: The HLS2 offers the same capabilities as the original SageHLS except for the capability to heat or cool the agarose gel cassettes. This has been deemed unnecessary for HLS-CATCH and supported applications.
Sage Science will continue to sell and support the SageHLS platform for researchers who wish to explore active temperature functionality with HLS-CATCH or other studies.
The SageHLS instrument includes a monitor, keyboard, and mouse. A CPU is built in; an external PC is not required.
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| SageHLS Specifications | |
| Electrophoresis voltage | 25V - 100V pulsed field and 150V constant |
| Optical detection | None |
| Power requirements | 100-240 VAC, 2.5 A, 50-60 Hz |
| Weight | 20 lbs / 9 kg |
| Dimensions | 10.5h x 13w x 10d (in) | 27h x 33w x 25d (cm), w/ closed lid |
Kits include 4 or 10 ea. disposable pre-cast gel cassettes. Cassette accommodate 2 samples. Some reagents must purchased separately.